Mechanical Engineering

Chris Rylander

 

Chris Rylander

Assistant Professor

Mechanical Engineering, School of Biomedical Engineering and Sciences
Corporate Research Center
Bldg XV, Suite 2000, MC 0493
1880 Pratt Drive
(540) 231-0964
(540) 231-9100 FAX
cgr@vt.edu

 

Education Research
Teaching
Experience
Honors
Publications

 

Education

Ph.D. Biomedical Engineering University of Texas - Austin 2005
M.S. Mechanical Engineering University of Texas - Austin 2002
B.S. Mechanical Engineering University of Texas - Austin 2000

 

Research

Dr. Rylander's Biomedical Optics & Devices Laboratory website

For more information please see Dr. Rylander's SBES website

  • Techniques and Devices to Modify Tissue Optical and Thermal Properties
  • Nanotechnology to Assist Laser Hyperthermia Therapy
  • Phase-Sensitive Optical Coherence Microscopy
  • Optical Measurement of Cell Membrane Permeability Parameters
  • Modeling Bio-Heat and Mass Transport
  • Optical Coherence Tomography (OCT) for In-vivo Imaging of Inflammation


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Teaching Activities

BMES 5014 Quantitative Physiology

Mathematical modeling, simulation, quantitative description of organ physiology and control. Numerical simulation of physiologic processes. Cell resting membrane potential, and nerve and muscle tissue. Regulation of cardiac output, venous return, and closed-loop control. Pressure-volume behavior of alveoli and respiratory ventilation control. Nephron countercurrent mechanism, and hemodialysis. Metabolism, internal heat generation and temperature regulation.

ME 3304 Heat and Mass Transfer

Comprehensive basic course in heat and mass transfer for mechanical engineering students. Principles of conduction, convection, and radiation with applications to heat exchangers and other engineering systems. Pre: 3105 or 3114; Co: 3404. (3H,3C). II,III.

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Experience

Assistant professor Virginia Tech
Blacksburg, VA		 April 2007 - Present
Engineer DermaLucent LLC, Austin, TX June 2006 - March 2007
Post-Doctoral Researcher University of Texas - Austin, TX September 2005 - May 2006

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Honors

  • Selected best student/resident paper submitted in the basic science section of the 23rd Meeting of the American Society for Lasers in Medicine and Surgery, April 2003

  • Selected runner-up for best student paper submitted at Cryo2002 Society for Cryobiology Annual Meeting, July 2002

  • Selected for NSF IGERT Program scholarship and graduate training in Cellular and Molecular Imaging for Diagnostics and Therapeutics

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Publications

Refereed Journal Articles

  • C.G. Rylander, O.F. Stumpp, T.E. Milner, N.J. Kemp, J.M. Mendenhall, K.R. Diller, A.J. Welch, "Dehydration mechanism of optical clearing in tissue," Journal of Biomedical Optics 11(4): 041117-1-7, 2006.

  • J. Kim, D.P. Dave, C.G. Rylander, J. Oh, and T.E. Milner, "Spatial refractive index measurement of porcine artery using differential phase optical coherence microscopy," Lasers Surg. Med. 38: 955-959, 2006.

  • C.G. Rylander, D.P. Dave, T. Akkin, T.E. Milner, K.R. Diller, A.J. Welch, "Quantitative phase-contrast imaging of cells with phase-sensitive optical coherence microscopy," Optics Letters 29(13): 1509-1511, 2004.

  • C.G. Rylander, K.R. Diller, T.E. Milner, A.J. Welch, "Measurement of chemical transport across individual cell membranes using optical path length imaging and modeling," ASME Journal of Biomechanical Engineering, In Preparation.

  • C.G. Rylander, T.E. Milner, J.S. Nelson, "Mechanical tissue optical clearing devices: Evaluation of enhanced light penetration in skin using OCT," Journal of Biomedical Optics, In Preparation.

Conference Proceedings

  • C.G. Rylander, T.E. Milner, K.R. Diller, A.J. Welch, “Mechanisms of optical clearing in cellular tissue,” Proc. SPIE 5695: 93-101, April 2005. 

  • A.J. Welch, C. Humphrey, G. Vargas, O.F. Stumpp, C.G. Rylander, “Creating the invisible man,” Proc. SPIE 5319: 285-290, July 2004.

  • J. Kim, D.P. Dave, C.G. Rylander, M.D. Feldman, S.L. Thomsen, T.E. Milner, “Spatial refractive index measurement of porcine artery using differential phase OCT,” Proc. SPIE 5316: 167-171, July 2004. 

  • C.G. Rylander, K.R. Diller, T.E. Milner, A.J. Welch, “Measurement of transient glycerol concentration in individual cells using optical low-coherence reflectometry,” Cryobiology 45: 237-238, 2002.

Posters and Presentations

  • C.G. Rylander, T.E. Milner, K.R. Diller, A.J. Welch, “Measurement of cellular transmembrane chemical transport using optical path length imaging and modeling,” 2005 ASME Summer Bioengineering Conference, Vail, June 2005.

  • C.G. Rylander, T.E. Milner, K.R. Diller, A.J. Welch, “Mechanisms of optical clearing in cellular tissue,” 22nd Annual Houston Conference on Biomedical Research, Houston, February 2005. 

  • C.G. Rylander, T.E. Milner, K.R. Diller, A.J. Welch, “Mechanisms of optical clearing in cellular tissue,” SPIE Conference Symposium on Biomedical Optics 2005, San Jose, January 2005. 

  • C.G. Rylander, T.E. Milner, K.R. Diller, A.J. Welch, “Quantification of transient transport of hyper-osmotic agents across cell membranes and resulting optical clearing using DPCOCM,” Gordon Special Conference on Lasers in Medicine and Biology, New Hampshire, July 2004. 

  • C.G. Rylander, T.E. Milner, K.R. Diller, A.J. Welch, “Spatial refractive index determination of individual cells using differential phase contrast optical coherence microscopy:  Optical path length measurements,” 23rd Meeting of the American Society for Lasers in Medicine and Surgery, Los Angeles, April 2003.   

  • C.G. Rylander, K.R. Diller, T.E. Milner, A.J. Welch, “Measurement of transient glycerol concentration in individual cells using optical low-coherence reflectometry,” Cryo2002 Society for Cryobiology Annual Meeting, Breckenridge, July 2002.

 

Patents

US provisional patent application entitled Tissue Clearing Techniques and Devices, #065715.0118


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